Believe it or not, Agents of SHIELD falls right in line with stereotypical mainstream procedural shows. Really a lot of TV is more high concept than most people think. There's been multiple shows of supernatural detectives (Medium, Dresden, Pushing Daisies). Plenty of paranormal investigation team shows (X-Files and it's copycats Fringe, Warehouse 13, and Sanctuary). Fairy-tale adaptations are now pretty huge with Once Upon a Time, Grimm, Sleepy Hollow, Teen Wolf, Supernatural, and Wizards versus Aliens (YES THIS IS A REAL THING...
LOOK IT UP NOW!). On top of all that, superheroes shows are actually no strangers to TV either. Really, they aren't. Especially the "realistic" non-costumed hero types.
Anyone remember Heroes? What about Syfy's Alphas? No? There's plenty more. The Batman spinoff Birds of Prey, James Cameron's Dark Angel, Mutant X, The Cape, Smallville, Arrow, Bionic Woman (yes I count that), NightMan, Blade: The Series (yes I count that too), WitchBlade, the Highlander TV spinoffs. (Most of these suck BTW and yes I've watched almost all of these...) and there's the British Misfits. Oh and The CW is premiering The Tomorrow People this coming TV fall season.
Which, as far as I can tell, is basically The CW's (shittier) version of the X-Men.
Anyways I can even go a little further with superhero stuff. If you'd like to count shows that are practically superhero stories but aren't written specifically with that genre in mind, you can easily count Person of Interest (seriously, this is the TV Dark Knight and it is GLORIOUS!), Painkiller Jane, Le Femme Nikita, and the last season of 24 (LOLJACKBAUERMASK!). These are not really a huge stretch from certain figures in comic books like The Punisher.
And I didn't even list the Saturday morning cartoons.
So I hoped I've showed you why I found people saying that everything about Agents of SHIELD is "new" and "unique" to be irritatingly inaccurate. The only thing unique about Agents of SHIELD is the fact that it's set in the Marvel universe. So really the flashy skin on top of it. Sure, Agents of SHIELD isn't generic like The Cape or Alphas. But under all that gloss and faux-novelty is a show that is a little more standard than most people would like to admit (or allow themselves to see).
So what is it about Agents of SHIELD that I found so standard? Let's take a quick look at the writing shall we?